NIGMS Mature Synchrotron Resources (MSR) for Structural Biology (P30 - Clinical Trial Not Allowed)

The National Institute of General Medical Sciences (NIGMS), under the U.S. Department of Health and Human Services, is forecasting the release of a funding opportunity announcement (FOA) for the Mature Synchrotron Resources (MSR) for Structural Biology program (PAR-26-029). This opportunity is classified under the P30 activity code and does not allow clinical trials. The initiative is part of NIGMS’s long-standing support for national research infrastructure, aiming to sustain advanced synchrotron-based tools and services that are essential for biomedical structural biology. The MSR program supports mature, well-established synchrotron beamline facilities that provide U.S.-based biomedical researchers with access to state-of-the-art X-ray technologies. These resources play a crucial role in generating and analyzing structural data that underpin numerous discoveries in molecular biology, enzymology, drug development, and other biomedical domains. Funded centers are expected to offer not only access to synchrotron beamlines but also specialized user training and expert assistance, ensuring that the national research community is well-equipped to utilize these high-end tools effectively. Funding under this opportunity will continue to support these facilities as critical components of the national research infrastructure. The resources are expected to maintain consistent operation, support remote and onsite data collection, and promote methodological innovations. The program encourages collaboration with researchers across various scientific disciplines and supports integration with other NIH structural biology initiatives. While full details regarding the funding amounts and budget structure have not yet been disclosed, the FOA explicitly states that no cost sharing or matching is required for applicants. Award amounts and the total program funding are yet to be announced. The program anticipates funding multiple awards, but no exact number is provided at this stage. The program falls under Assistance Listing Number 93.859 for Biomedical Research and Research Training. Eligibility for the opportunity is inclusive, spanning a wide range of applicant types. Eligible applicants include public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses, for-profit organizations, state and local governments, tribal organizations (both federally recognized and other), independent school districts, and several other entity types. U.S. territories and regional organizations are also eligible, and federal agencies may apply. This reflects NIH’s commitment to supporting diverse organizations engaged in biomedical research infrastructure. The FOA is forecasted to be officially posted on August 13, 2026, with an expected application due date of October 13, 2026. Both the award and project start dates are set for July 1, 2027. As this is a forecasted opportunity, full submission mechanics and evaluation criteria will be disclosed once the final FOA is issued. Inquiries regarding the program can be directed to the official program email, [email protected].