Grants for Small businesses - Science and Technology

This funding opportunity supports innovative research projects aimed at developing new therapies for Amyotrophic Lateral Sclerosis (ALS), encouraging high-risk ideas that include biomarker development to guide future clinical applications.

This funding opportunity supports research and technology development in advanced telecommunications systems for various industries, including healthcare and transportation, targeting academic institutions, nonprofits, and businesses to foster innovation and collaboration.

To implement a project aimed at advancing U.S. foreign policy and national security priorities by supporting initiatives that make decision-making structures and processes in fragile, conflict, or crisis-affected contexts more reflective of and responsive to the needs and perspectives of partner states to ensure strategic trade control systems meet international standards and by engaging on bilateral, regional and multilateral levels with foreign governments to aid in the establishment of independent capabilities to regulate transfers of weapons of mass destruction, WMD-related items, conventional arms, and related dual-use items, and to detect, interdict, investigate, and prosecute illicit transfers of such items.

The EHDA supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the TSC research field. The studies supported by this award mechanism are expected to generate preliminary data for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on a strong scientific rationale and study design. Applications should demonstrate the ability to achieve interpretable results in the absence of preliminary data supporting the hypothesis.The following are important aspects of the EHDA: Innovation: Innovative research may introduce a new paradigm, challenge existing paradigms, examine existing problems from new perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative and is not consistent with the intent of the award mechanism. Although not all-inclusive, the following examples are ways in which the proposed research project may be innovative: Explores a novel idea and/or research question in TSC research and/or patient care. Uses or develops novel methods or technologies to address a question in TSC research and/or patient care. Applies or adapts existing methods or technologies for novel TSC research or clinical purposes that differ fundamentally from those originally intended.

This funding opportunity supports a wide range of organizations in developing innovative treatments and testing strategies to prevent and modify epilepsy and other neurological disorders.

This funding opportunity is designed to support U.S.-based small businesses in developing innovative quantum computing solutions for complex energy-related challenges in computational chemistry and materials science.

This program provides financial support to small businesses in Tazewell and Buchanan Counties, Virginia, to enhance their digital capabilities and online presence.

The Southern STEM Network Grant VI, administered by the Nevada Governor’s Office of Science, Innovation, and Technology (OSIT), aims to support innovative initiatives that help develop an educated, skilled, and diverse STEM workforce in Southern Nevada. Projects should address increased participation in high-quality STEM programs from underserved groups, raise awareness about STEM opportunities, and ensure high-quality STEM education with engaged business partners across all counties, cities, and districts. Funding is available up to $50,000, with applications due by June 28, 2024. Eligible projects include pilot programs, scaling up existing programs, or extending successful initiatives from other regions.

This grant provides funding for organizations to facilitate college tours for underserved high school students in Washington, D.C., helping them explore Historically Black Colleges and Universities and prepare for higher education.

This grant provides funding for innovative technologies that improve the Navy and Marine Corps' electronic warfare and surveillance capabilities, targeting researchers and companies developing advanced signal processing, countermeasures, and ISR systems.

This funding opportunity supports partnerships that include domestic academic institutions to develop innovative technologies for extracting and refining rare earth elements from unconventional sources, enhancing the U.S. supply chain and reducing environmental impact.

This grant provides funding for early-phase clinical trials aimed at improving treatments for service-connected eye injuries and visual dysfunction in military personnel and veterans.

The PRMRP Technology/Therapeutic Development Award (TTDA) is a product-driven award mechanism intended to provide support for the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the FY24 PRMRP Topic Areas and one of the FY24 PRMRP Strategic Goals. Products in development should be responsive to the health care needs of military Service Members, Veterans, and their Families. The product(s) to be developed under the PRMRP TTDA mechanism may be a tangible item, such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product. (A knowledge product is a non-materiel product that addresses an identified need in a topic area, is based on current evidence and research, aims to transition into medical practice, training, tools, or to support materiel solutions [systems to develop, acquire, provide, and sustain medical solutions and capabilities], and educates or impacts behavior throughout the continuum of care, including primary prevention of negative outcomes.)The Technology/Therapeutic Development Award is not intended for basic research. Applicants generating preliminary data, basic research, performing high-risk/high-gain studies should consider one of the other FY24 PRMRP program announcements being offered. For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.

The City of Alhambra in California is offering a Small Business Assistance Grant Program to support local small businesses affected by the COVID-19 pandemic. Eligible businesses must either serve a U.S. Department of Housing and Urban Development (HUD) defined low- and moderate-income area within Alhambra or be owned by low- and moderate-income individuals.Groups of neighbors must find a host organization to sponsor the project and act as the project fiduciary. Applications are accepted year-round until funds are exhausted.

This grant provides funding for researchers, especially early-career scientists and students, to develop and test new technologies for studying solar and space physics through low-cost suborbital flights.

The Regional Site Readiness Program’s Planning Grant, funded by the Illinois Department of Commerce and Economic Opportunity, offers $100,000 to $500,000 to local governments, economic development organizations, nonprofits, for-profit organizations, and private landowners for planning and due diligence activities aimed at preparing industrial and manufacturing sites for future development across all counties in Illinois.

This program provides financial support to established small businesses in downtown North Wilkesboro and Wilkesboro, North Carolina, to enhance their operations through equipment upgrades, physical space improvements, and e-commerce development.

Public Health – Seattle & King County is offering a grant of $100,000 to $500,000 for projects that support diverse youth mental health providers, particularly those connected to LGBTQIA and BIPOC communities, with the aim of increasing access to mental health resources, improving retention, and supporting diverse providers in King County, Washington.

This funding opportunity supports a variety of organizations in developing innovative technologies to identify and target senescent cells, which could lead to new treatments for age-related diseases.

The 80MSFC24M0001 Cooperative Agreement Notice is a grant aimed at fostering partnerships with U.S. industry and academic/non-profit organizations to develop technologies that enhance the commercial space sector, support future NASA missions, and promote the U.S. as a leader in aeronautical and space science, with financial support provided by NASA.