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Grants for Nonprofits - Federal

Explore 5,539 grant opportunities

FY 2026 America First U.S. Speaker Program
$2,736,259
U.S. Department of State (Bureau Of Educational and Cultural Affairs)
Federal

Application Deadline

May 26, 2026

Date Added

Mar 27, 2026

This funding opportunity supports U.S.-based nonprofit organizations and educational institutions to engage international audiences on key policy issues through expert-led programs focused on America First priorities.

International Development
Nonprofits
Infrastructure Systems and People (ISP)
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 18, 2025

This program provides funding for innovative research that improves the design and resilience of critical infrastructure systems to better protect communities from various disruptions.

Infrastructure
Nonprofits
Targeted Genome Editor Delivery (TARGETED) Challenge
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 4, 2026

Date Added

Dec 24, 2025

This grant provides funding to researchers and innovators developing advanced delivery systems for genome editing technologies, particularly targeting hard-to-reach tissues and overcoming barriers like the blood-brain barrier.

Science and Technology
For profit organizations other than small businesses
Injury Prevention and Control Research and State and Community Based Programs - RFA-SH-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 19, 2023

This funding opportunity provides financial support to a wide range of organizations, including state governments, universities, and nonprofits, to develop and implement programs focused on preventing injuries and promoting public health in communities across the U.S.

Health
State governments
Focused Technology Research and Development (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 22, 2026

Date Added

Nov 15, 2024

This funding opportunity supports innovative projects that develop new tools and technologies to advance biomedical research, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

Health
State governments
Spurring Projects To Advance Energy Research And Knowledge Swiftly (SPARKS)
$500,000
U.S. Department of Energy (Advanced Research Projects Agency Energy)
Federal
Rolling

Application Deadline

Sep 30, 2029

Date Added

Nov 9, 2023

This funding opportunity supports innovative energy research projects that have the potential to significantly transform energy technologies, targeting a wide range of applicants including educational institutions, nonprofits, and small businesses.

Science and Technology
Individuals
Mechanics of Materials and Structures
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jun 12, 2018

This program provides funding for researchers exploring the behavior of materials and structures under various conditions, focusing on innovative approaches in mechanics, computational methods, and experimental techniques.

Science and Technology
Public and State controlled institutions of higher education
Ocean Technology and Interdisciplinary Coordination
Contact for amount
National Science Foundation
Federal

Application Deadline

Feb 15, 2027

Date Added

Mar 5, 2025

This program provides funding for researchers to develop innovative oceanographic technologies and improve interdisciplinary collaboration in ocean science.

Science and Technology
Public and State controlled institutions of higher education
Rfa-Tp-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Nov 26, 2025

This funding opportunity provides financial support to a variety of organizations, including state governments, universities, and nonprofits, to implement innovative public health programs focused on preventing injuries and promoting safety in communities.

Health
State governments
Securing Artificial Intelligence for Battlefield Effective Robustness (SABER)
Contact for amount
U.S. Department of Defense (DoD)
Federal

Application Deadline

Not specified

Date Added

Mar 18, 2025

This grant provides funding to U.S. organizations capable of handling classified information to develop and enhance security measures for AI systems used in military applications, focusing on identifying and mitigating vulnerabilities in battlefield technologies.

Science and Technology
For profit organizations other than small businesses
Biophotonics
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Apr 5, 2023

This funding opportunity supports innovative engineering research that combines photonics with biology and medicine to develop advanced diagnostic and therapeutic technologies.

Science and Technology
Private institutions of higher education
Condensed Matter and Materials Theory
$15,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant provides funding for U.S. researchers at universities and nonprofit institutions to conduct innovative theoretical and computational studies on materials, aiming to advance our understanding of their properties and behaviors.

Science and Technology
Nonprofits
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 5, 2026

Date Added

Nov 7, 2024

This funding opportunity supports collaborations between academic researchers and industry partners to develop and validate advanced imaging technologies that improve cancer detection and treatment.

Education
State governments
Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Apr 3, 2026

Date Added

May 19, 2023

This grant provides researchers with access to advanced facilities and technical support for developing non-hormonal contraception and reproductive health products, without direct funding.

Health
State governments
NSF Research: Correctness for Scientific Computing Systems
$800,000
National Science Foundation
Federal

Application Deadline

Aug 11, 2026

Date Added

May 10, 2024

This funding opportunity supports U.S.-based researchers and institutions in developing verified correctness for high-performance scientific computing systems, ensuring reliable and accurate scientific simulations and analyses.

Science and Technology
Public and State controlled institutions of higher education
OIA Maintenance Assistance Program 2026
$4,375,000
U.S. Department of the Interior
Federal

Application Deadline

May 18, 2026

Date Added

Mar 17, 2026

This grant provides funding to local governments and nonprofit organizations in U.S. territories and freely associated states for infrastructure maintenance and capacity-building projects that enhance public services and support economic development.

Infrastructure
City or township governments
FY 2024 2026 - Broad Agency Announcement (BAA) Announcement Type: Initial
Contact for amount
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Sep 30, 2026

Date Added

Aug 15, 2024

This grant provides funding for innovative research, education, and outreach projects that promote ocean exploration and enhance environmental literacy, particularly in diverse and hybrid learning environments.

Environment
Public and State controlled institutions of higher education
Long Range Broad Agency Announcement (LRBAA) 24-01
Contact for amount
U.S. Department of Homeland Security (DHS), Science and Technology Directorate (S&T)
Federal
Rolling

Application Deadline

May 31, 2029

Date Added

Mar 18, 2025

This grant invites industry and academic researchers to propose innovative solutions that enhance homeland security across various mission areas, including counterterrorism, cybersecurity, and public safety.

Science and Technology
For profit organizations other than small businesses
ROSES25: A.3 NASA ISRO Synthetic Aperture Radar Mission Data, Applications, Research, and Technology Team
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

May 14, 2026

Date Added

Feb 13, 2026

This grant provides funding for U.S.-based research institutions to develop applications and technologies using advanced radar data from a collaborative NASA and ISRO mission, focusing on monitoring Earth's land and ice changes.

Science and Technology
Public and State controlled institutions of higher education
Methodology, Measurement, and Statistics
$3,760,000
National Science Foundation
Federal

Application Deadline

Aug 27, 2026

Date Added

Feb 7, 2025

This program provides funding for innovative research in statistical methods and data collection techniques that benefit social, behavioral, and economic research, particularly through collaboration with federal statistical agencies.

Information and Statistics
Public and State controlled institutions of higher education